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De Wit, Harriet
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overview The de Wit laboratory investigates the subjective, behavioral and physiological effects of drugs of abuse in healthy human volunteers. Some studies are designed to identify individual differences and risk factors for excessive use, and others to determine the effects of drugs on mood, psychomotor and cognitive performance, and brain activity. Another major interest is the study of conditioned drug effects, or cues, that influence future drug use.
One or more keywords matched the following items that are connected to De Wit, Harriet
Item TypeName
Concept Cross-Sectional Studies
Concept Drug Evaluation, Preclinical
Concept Models, Genetic
Concept Models, Theoretical
Concept Mice, Inbred C57BL
Concept Cohort Studies
Concept Linear Models
Concept Models, Animal
Concept Mice, Inbred DBA
Concept Case-Control Studies
Concept Twin Studies as Topic
Concept Cross-Over Studies
Concept Genetic Association Studies
Concept Mice
Concept Logistic Models
Concept Disease Models, Animal
Concept Follow-Up Studies
Concept Longitudinal Studies
Concept Models, Psychological
Concept Retrospective Studies
Concept Drug Users
Academic Article The effects of ethanol on the relative preference for cigarettes.
Academic Article Effects of triazolam at three phases of the menstrual cycle.
Academic Article Naltrexone does not block the subjective effects of oral Delta(9)-tetrahydrocannabinol in humans.
Academic Article Effects of d-amphetamine and ethanol on a measure of behavioral inhibition in humans.
Academic Article Responses to oral delta9-tetrahydrocannabinol in frequent and infrequent marijuana users.
Academic Article Delay or probability discounting in a model of impulsive behavior: effect of alcohol.
Academic Article Preference procedures for testing the abuse liability of drugs in humans.
Academic Article Effects of THC on behavioral measures of impulsivity in humans.
Academic Article Comparison of the subjective effects of Delta(9)-tetrahydrocannabinol and marijuana in humans.
Academic Article Dual determinants of drug use in humans: reward and impulsivity.
Academic Article Differential subjective effects of D-amphetamine by gender, hormone levels and menstrual cycle phase.
Academic Article The reinstatement model of drug relapse: history, methodology and major findings.
Academic Article Association between the casein kinase 1 epsilon gene region and subjective response to D-amphetamine.
Academic Article Subjective effects of slow-release bupropion versus caffeine as determined in a quasi-naturalistic setting.
Academic Article Subjective, behavioral, and physiological effects of acute caffeine in light, nondependent caffeine users.
Academic Article Behavioral and subjective effects of ethanol: relationship to cerebral metabolism using PET.
Academic Article Personality and gender differences in effects of d-amphetamine on risk taking.
Academic Article Challenges for translational psychopharmacology research--some basic principles.
Academic Article Further evidence of association between amphetamine response and SLC6A2 gene variants.
Academic Article Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans.
Academic Article Genetics of caffeine consumption and responses to caffeine.
Academic Article More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine.
Academic Article Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.
Academic Article Combined effects of acute, very-low-dose ethanol and delta(9)-tetrahydrocannabinol in healthy human volunteers.
Academic Article Translational genetic approaches to substance use disorders: bridging the gap between mice and humans.
Academic Article Effects of delta-9-tetrahydrocannabinol on evaluation of emotional images.
Academic Article Hormonal, cardiovascular, and subjective responses to acute stress in smokers.
Academic Article Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of D-amphetamine: an exploratory pharmacogenetic study using healthy volunteers.
Academic Article Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
Academic Article Amping up effort: effects of d-amphetamine on human effort-based decision-making.
Academic Article Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans.
Academic Article Assessing pentobarbital preference in normal volunteers using a cumulative dosing procedure.
Academic Article Effects of ethanol, diazepam and amphetamines on cerebral metabolic rate: PET studies using FDG.
Academic Article Serotonin transporter genotype and acute subjective response to amphetamine.
Academic Article Lack of association between COMT and working memory in a population-based cohort of healthy young adults.
Academic Article Relationship of self-reported and acute stress to smoking in emerging adult smokers.
Academic Article Pre-encoding administration of amphetamine or THC preferentially modulates emotional memory in humans.
Academic Article Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism.
Academic Article Does COMT genotype influence the effects of d-amphetamine on executive functioning?
Academic Article Personality traits modulate emotional and physiological responses to stress.
Academic Article Contextual conditioning enhances the psychostimulant and incentive properties of d-amphetamine in humans.
Academic Article Genetic factors modulating the response to stimulant drugs in humans.
Academic Article Using conditioned place preference to identify relapse prevention medications.
Academic Article Sex differences in impulsive action and impulsive choice.
Academic Article Quantifying reinforcement value and demand for psychoactive substances in humans.
Academic Article ADHD, impulsivity and alcohol abuse: methods, results, and implications.
Academic Article Effects of MDMA and Intranasal oxytocin on social and emotional processing.
Academic Article Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.
Academic Article A Preliminary Investigation of Individual Differences in Subjective Responses to D-Amphetamine, Alcohol, and Delta-9-Tetrahydrocannabinol Using a Within-Subjects Randomized Trial.
Academic Article Interrelationships among parental family history of substance misuse, delay discounting, and personal substance use.
Academic Article Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium.
Academic Article The latent structure of impulsivity: impulsive choice, impulsive action, and impulsive personality traits.
Academic Article Insulin administered by needle-free jet injection corrects marked hyperglycaemia faster in overweight or obese patients with diabetes.
Academic Article Virtual reality conditioned place preference using monetary reward.
Academic Article Associations Between Behavioral and Neural Correlates of Inhibitory Control and Amphetamine Reward Sensitivity.
Academic Article Alcohol and pharmacologically similar sedatives impair encoding and facilitate consolidation of both recollection and familiarity in episodic memory.
Academic Article Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry.
Academic Article Does human language limit translatability of clinical and preclinical addiction research?
Academic Article Pharmacological challenge studies with acute psychosocial stress.
Academic Article Genome-Wide Association Studies of Impulsive Personality Traits (BIS-11 and UPPS-P) and Drug Experimentation in up to 22,861 Adult Research Participants Identify Loci in the CACNA1I and CADM2 genes.
Academic Article Acute Subjective and Behavioral Effects of Microdoses of Lysergic Acid Diethylamide in Healthy Human Volunteers.
Academic Article Association between impulsivity traits and body mass index at the observational and genetic epidemiology level.
Academic Article Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.
Academic Article ?9-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial.
Academic Article Using pharmacological manipulations to study the role of dopamine in human reward functioning: A review of studies in healthy adults.
Academic Article Effects of Acute Drug Administration on Emotion: A Review of Pharmacological MRI Studies.
Academic Article Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study.
Academic Article Effects of alcohol on sleep and nocturnal heart rate: Relationships to intoxication and morning-after effects.
Grant Craving During Smoking Abstinence: Does it Abate or Incubate?
Grant DRUGS OF ABUSE ON REGIONAL CEREBRAL METABOLISM AND MOOD
Grant Memory effects of stimulant drugs in humans
Grant Nicotinic Involvement &Consumption of Alcohol in Humans
Grant BLOCKADE OF METHAMPHETAMINE SUBJECTIVE EFFECTS IN HUMANS
Grant Drug Abuse and Impulsivity: Human Laboratory Models
Grant Is Ecstasy an Empathogen? Effects of MDMA on Social and Emotional Processing
Grant PHARMACOLOGIC STUDIES OF MARIJUANA &ALPHA THC IN HUMAN
Grant Inhibitory Control and Drug Reward in Humans
Grant The genetic basis of impulsive behavior in humans
Grant BEHAVIORAL ECONOMICS OF DRUG CHOICE
Academic Article Greater subjective effects of a low dose of LSD in participants with depressed mood.
Academic Article Unique effects of sedatives, dissociatives, psychedelics, stimulants, and cannabinoids on episodic memory: A review and reanalysis of acute drug effects on recollection, familiarity, and metamemory.
Academic Article Microdosing Psychedelics: Current Evidence From Controlled Studies.
Search Criteria
  • Preclinical
  • studies
  • using
  • mouse
  • models